Current Research (Since 2014-today)

Our current research focuses on the cellular signalling and target identification of novel natural compounds which can control cancers and neurodegenerative diseases. To this aim we utilize different in vivo models (Danio rerio, Caenorhabditis elegans, Mus musculus and Rattus) and applications of nanomedicine. The long term research focus on the following:

1.     To elucidate the interplay between apoptosis and autophagy signalling pathway involved in programmed cells death. Here the goal is to identify the potent anti-cancer drug to understand the cellular and molecular mechanisms involved in the development and survival of cancer cells. This research is funded by National Research Foundation of Korea.

2.     Modulation of lysosomal biogenesis by cathepsins (B, D, L, C, G) with emphasis on human colorectal cancer. This research was funded by the Korea Research Fellowship, South Korea (ended on Feb 2019). [Work still in progress]

3.     Autophagy and lysosomal function in neurological disorders. (Not in receipt of any grant).

4.     Structural and functional characterization of splicing factors in colon cancer. This research is funded by Korea Research Fellowship, South Korea (Oct, 2019-Dec, 2023)